Loss of miR-301a and miR-454 expression would therefore render ineffective a proposed feedback loop controlling ET-1 and PAI-1 levels.
It described as "ineffective" a device proposed by the Thai construction company carrying out the project to allow fish to bypass the dam.
In order to avoid the detailed 3D modelling of nails (or screws) using solid elements, which is costly ineffective, the authors proposed and developed an approach based on beam-to-solid coupling where the nails (or screws) were modelled using one-dimensional beam element, while the assembled timber members were modelled using solid elements.
In 2002, the five members of the Public Oversight Board (POB), which oversaw ethics within the accounting profession, resigned after critics deemed the board ineffective and the SEC proposed developing a new panel, the Public Company Accounting Oversight Board (PCAOB).
Yes, Wall Street is in denial about its behavior, but so are the regulators because of the ineffective solutions they propose.
WASHINGTON (The Borowitz Report) – Calling the Obama Administration's actions against the soccer organization "weak and ineffective," Senator John McCain on Thursday proposed military action to "dismantle and destroy FIFA once and for all".
Those states have said that central elements of the agreement -- greater disclosure of software code, nondiscrimination against rivals and computer makers, and limits on the ability of Microsoft to leverage its monopoly in the server markets -- have overly broad exceptions that would make the proposed settlement largely ineffective.
However, in reality, there are two important scenarios in which this assumption is violated, but in such a way that the outlier removal mechanisms of the proposed method are ineffective.
The American College of Obstetricians and Gynecologists, the American Academy of Pediatrics, and other major medical groups were quick to condemn Big Horn County's proposed crackdown as "ineffective" and "harmful".
Michael Koskoff, a prominent Connecticut malpractice lawyer, called the proposed $250,000 cap an ineffective "one size fits all" solution.
