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A potential reason behind this is a resistance to rifampicin that may have developed, and thus resulted in the ineffective outcome of using an MBC dose of rifampicin, as compared to that of gentamicin.
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The ineffective, outcome-based payment structure also constrained ASHAs' work output [ 43], since some ASHAs tended to focus more on those activities which attract payment, such as provision of contraceptives and facility-based deliveries, at the expense of other essential activities such as general health promotion activities at community level [ 6, 43, 49].
Furthermore, it remains unclear whether poor adherence is the reason for ineffective treatment outcome, or whether patients' poor adherence is the results of lack of immediate therapeutic benefits of PT treatment [ 28].
Treatment with too few drugs and for a too short duration has been shown to result in ineffective treatment outcomes of patients.
There is some evidence that the negative effects of depression on diabetes, 4, 5 inability to self-manage, 2 poor glycemic control, 4, 6, 7 and ineffective treatment outcomes 8 can be predicted by diabetic distress.
(Interestingly, the buildings we saw were the second iteration of office redesign. The first was for complete open space, which they found to be ineffective. One unintended outcome was a "library effect," where people felt discouraged from having open communication). The current iteration is being expanded to other buildings in the Microsoft campus.
Possible explanations offered for interventions found to be ineffective were inappropriate outcome measures; non-specific goals that do not target needs; and ineffective research evaluation designs [ 13, 39].
Is it possible that ineffective and poor outcomes of inpatient tocolytic treatments are associated with the physician and institutional variations observed in this study?
However, two multi-center, randomized controlled trials (RCTs) and two large observational studies have shown the liberal use of blood transfusions, with the goal of maintaining relatively arbitrary Hb concentrations (e.g. 10 g/dl), to not only be ineffective at improving outcomes, but also potentially harmful [ 10, 11, 25, 26].
However, the outcome is ineffective as the spatial dispersion of fillers within the SMP is inhomogeneous and leads to performance loss.
Our research setting does not allow us to determine whether the relatively modest outcome reflects ineffective treatment methods or defective compliance of patients with the recommended therapy.
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