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These deals will have illusory and ineffective options for environmental and labor protections and human rights.
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The possibility of a government that serves the interests of incumbent politicians and special interests rather than the public remains as real a danger now as it was a century ago, and the initiative provides an important alternative to the crude and often ineffective option of removing an unresponsive officials at the polls.
Surgery is the treatment of choice in the developing world as poor compliance makes medical treatment an ineffective option.
Numerous "good" surgical practices have evolved into "standard of care" without being randomized against placebo or ineffective treatment options [ 10].
The majority of HCC patients are diagnosed in advanced stages with ineffective therapeutic options and unfavorable prognosis [ 43].
This largely explains the lack of understanding of its cause and mechanisms and the exceedingly restricted and largely ineffective therapeutic options available for medical therapy.
In 2012, approximate 15%~20% of all breast cancer cases were diagnosed as TNBC [ 3], which had limited or ineffective treatment options.
Such high mortality rates are ascribed to disease recurrence despite cervical resection as well as ineffective treatment options for advanced disease.
These results are particularly concerning given that obese children/adolescents with prediabetes can progress to develop diabetes rapidly, in just 21 months (5), and are then faced with limited and relatively ineffective treatment options for T2D (6).
HCV infection is the leading indicator for liver transplantation in the developed world therefore research into identifying targets for therapeutic intervention is vital and has been stimulated by the limited ineffective therapy options and the lack of vaccines.
Given the significant rise in childhood T2D and the limited and relatively ineffective treatment options (6), these findings underscore the critical need for better understanding of the pathophysiological factors that may contribute to dysregulated neural control of eating, thereby perpetuating obesity and predisposing adolescents to prediabetes and rapid progression to T2D.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com