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The phrase "ineffective against" is correct and can be used in written English.
You can use it when you want to describe something that is not able to stop or block something else. Example: The old security system was ineffective against modern hacking techniques.
Exact(59)
He, too, was ineffective against Howard.
They are, however, ineffective against viruses.
Economic sanctions are ineffective against totalitarian regimes.
They are ineffective against viruses.
"It's ineffective against Barack Obama right now.
Has it been ineffective against them like everything else? Absolutely.
Japanese defensive missiles would have been ineffective against it.
Subsequently his ring's power became ineffective against anything coloured yellow.
(Antibiotics, of course, are ineffective against a viral infection).
He will hardly be as ineffective against Germany on Thursday night – a fixture he will relish.
The tactic was particularly ineffective against Randy Moss, who finished with 179 yards and 2 touchdowns.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com