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Carotenoids are plant secondary metabolites with a range of beneficial physiological, health and industrial traits.
Our work revealed thermophilic-bacteria specific features of adaptive evolution and demonstrated a rational strategy to engineer co-evolving industrial traits.
Therefore, this study revealed thermophilic-bacteria specific features of adaptive evolution and demonstrated a rational strategy to engineer the co-evolution of industrial traits.
Recently, the MET10 G176allelele, present in one of the low-H2S strains described by Cordente et al. (2009), was found to have a strong dominant effect, which allowed the use of this strain in the breeding of new interspecific hybrids with a low-H2S production phenotype and other desired industrial traits (Bizaj et al. 2012).
Population genomics revealed a close relationship between man and yeast (Liti et al. 2009), and as useful industrial traits have been selected for over time, some consider that S. cerevisiae has been domesticated for brewing, baking, and winemaking (Legras et al. 2007; Verstrepen et al. 2006).
The growth of W on sucrose, in combination with its many other desirable industrial traits (fast growth rate, growth to high cell densities, lack of adhesins which result in clumping, lack of antibiotic markers, and relative resistance to environmental stresses) also place E. coli W as a preferred strain for industrial biotechnology applications.
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Evolutionary engineering has been used to improve key industrial strain traits, such as carbon source utilization, tolerance to adverse environmental conditions, and resistance to chemical inhibitors, for many decades due to its technical simplicity and effectiveness.
Ultimately, engineering productive industrial biocatalysts with tolerance traits will be a pervasive biotechnological problem, and rationally engineering these traits will require an understanding of interacting genes and biological processes that affect tolerance.
Biochemical characterization of a specific enzyme from one organism to other is one of the ways to search for enzymes with better traits for industrial applications.
Finally, such a mutant may be employed for improving its desirable characteristics through evolutionary engineering methodologies in order to speed the fixation and breeding of the genetic traits with industrial interest.
Comparison of an enzyme activity across different species (Taylor et al. 2002), screening of enzymes with random mutations (Cherry and Fidantsef 2003) and introduction of specific mutations in the enzymes (Neylon 2004; Cherry and Fidantsef 2003) are some of the methods to obtain enzymes for industrial use with desirable traits for various industrial applications.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com