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Since Eef1a2 is not expressed in normal plasma cells, our findings suggest that inappropriate expression of EEF1A2 in B cell differentiation may contribute to the induction, progression or survival of a high proportion of primary PCT.
The pathogenesis of CIA follows three phases: induction, progression and resolution [ 17].
We will discuss the role of apoptosis and its deregulation during the induction, progression and maintenance of malignant disease.
Nevertheless, Fgfs show a multitude of properties in vitro that suggest that they have the potential to contribute to the induction, progression and metastasis of breast cancer.
This evidence points towards progesterone and its related signaling pathways as important players in the induction, progression and maintenance of the neoplastic phenotype in the mammary gland [ 1].
Impairment of p53 signaling by gene mutation or gene silencing/loss has been shown to contribute to the induction, progression and/or recurrence of many tumor types and can confer resistance to tumor therapy.
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Chronic inflammation is a central pathogenic mechanism of atherosclerosis induction and progression.
Iron is suspected to be involved in the induction and/or progression of various human tumors.
Molecular biology opened new vistas for cancer treatment as new pathways and targets that are involved in cancer induction and progression are becoming accessible.
Excessive production of ROS plays a crucial role in the induction and progression of several diseases such as the liver [26].
Therefore, most of the data on drugs targeting EMT has to be regarded as preliminary, and further research is needed to identify valuable pharmacologic targets during the induction or progression of the EMT process.
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