Sentence examples similar to induction of telomerase expression from inspiring English sources

Collectively, these results suggested that the upregulation of telomerase expression was sufficient to increase telomere length during the rapid cellular proliferation associated with the regeneration process, but after reclipping telomere length was not maintained, except in very young fish (3 months old) that show a robust telomerase induction.

We observed a significant decrease of telomerase expression with aging (Fig. 6C), confirming our previous results.

The inefficient activation of telomerase expression in oldest fish might be responsible for this behaviour.

They concluded that even in glioblastomas that show positivity for telomerase expression, there is variability in the level of telomerase expression from region to region within the tumour.

The inhibition of telomerase expression by tamoxifen is dependent on the presence of estrogen receptors [ 41].

Deregulation of telomerase expression in somatic cells may be involved in oncogenesis.

Figure 4B shows activity assays from cell lines with different levels of telomerase expression.

In this study, we determined the effect of Cephalotaxus griffithii needle (CGN) extract on human cancer cells in terms of antiproliferation, cell cycle regulation, apoptosis induction and telomerase expression.

We have also reported that overexpression of Bmi-1 leads to the induction of telomerase activity, reduction of p16INK4a expression, and immortalization of normal nasopharygeal epithelial cells (NPECs)[ 16].

Thus, the induction of telomerase activity by etoposide is independent of transcription of hTERT mRNA and probably based on post-transcriptional modification, for example of hTERT.

Bmi-1 overexpression leads to activation of human telomerase reverse transcriptase transcription and induction of telomerase activity in immortalized mammary epithelial cells[ 15].