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The influence of environment on the induction of sensitization to the psychomotor activating effects of intravenous cocaine in rats is dose-dependent.
When an EtOH challenge was administered 2 weeks following the induction of sensitization, HS, but not LS, mice showed a robust increase in glutamate levels (67%, P < 0.01) as measured by in vivo microdialysis.
Specifically, we compared the ability of contextual cues (a distinct test environment) and discrete cues (light, tone and/or odor), which both reliably predict drug administration, to promote the induction of sensitization.
For example, the importance of skin exposure as a route for induction of sensitization to peanut is still under debate.
In an animal study, triptans effectively prevented the induction of sensitization in central trigemino vascular neurons but not in meningeal nociceptors [47], which could indicate that triptans act on presynaptic 5-HT1B/1D receptons on the central terminals of meningeal nociceptors.
To test the specific contribution of saccharin consumption to the induction of sensitization in the S+/C+ condition, rats initially tested under the S+/C- condition were tested under the S+/C+ condition on day 16.
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The results of in vivo animal testing for MMA skin sensitization are presented in Table 3, which shows the test species, test methods for induction and elicitation of sensitization, the vehicle used for induction and elicitation, and the test results described by the individual authors.
The results showed that lesions of the medial prefrontal cortex (mPFC) blocked acute morphine-induced hyperactivity and the induction of behavioral sensitization, but the lesions had no effect on the expression of behavioral sensitization.
When animals were exposed to SEB and food antigen ovalbumin concurrently as we reported previously [ 17], intestinal sensitization was induced whereas those animals exposed to SEB or ovalbumin alone did not show any signs of intestinal sensitization, implicating that SEB may act as an adjuvant in the induction of intestinal sensitization with food antigens.
It should be noted here that the possibility that rapamycin is damping down a local inflammatory response in the paw, and so reducing inflammatory sensitivity is unlikely as the mechanical sensitivity in nerve injury models arises from the induction of central sensitization and the amplification of A-fiber responses-not local inflammation.
Ceftriaxone prevents the induction of cocaine sensitization and produces enduring attenuation of cue- and cocaine-primed reinstatement of cocaine-seeking.
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elicitation of sensitization
induction of gene
induction of anaesthesia
induction of cancer
induction of apoptosis
induction of anesthesia
induction of progesterone
induction of differentiation
induction of proceptivity
induction of callus
induction of root
induction of inflammation
induction of haemodialysis
induction of reactive
induction of acidosis
induction of biofilm
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Justyna Jupowicz-Kozak
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