Sentence examples for induction of interferon from inspiring English sources
Type I IFN signaling is characterized by an acute strong induction of interferon stimulated genes (ISGs) and confers fast antiviral protection.
This suggests that altered RNA capping increases virus' sensitivity to interferon-induced antiviral factors rather than induction of interferon signaling.
However, DENV also induces a down-regulation of the JAK/STAT pathway, inhibiting the induction of interferon regulated genes.
Only the ineffective shRNA, which formed an improper hairpin when analysed in silico, induced an antiviral response as measured by induction of interferon (ifnphi1) and Mx (MxA) genes.
In contrast, induction of interferon γ in response to lipopolysaccharide was similar in control subjects (78.0%) and vulvar vestibulitis patients (82.1%).
The innate immune protein Stimulator of interferon genes (STING) promotes the induction of interferon beta (IFN-β) production via the phosphorylation of its C-terminal tail (CTT) by TANK-binding kinase 1 (TBK1).
There was a significant association between reactivity against Ro, La, Smith and RNP and the induction of interferon-α with serum and necrotic cell material (p=0.035).
Bacterial DNA has a variety of immunostimulatory activities, such as the activation of B cells and natural killer cells, the induction of interferon-γ, and the induction of Th1-type immune responses.
Inclusion of 2′-O-methyluridine residues in the loop region was associated with 1.6- to 2.4-fold lower induction of interferon-α than was siRNA, without loss of gene-silencing activity.
Studies in gnotobiotic mice have shown that the host epithelial tissue response to co-colonization by commensal bacteria is the synergistic induction of interferon-responsive genes [14].
