Exact(3)
It is thus plausible that CDDO-MA may very well enable Michael's addition to its target Keap1 which is the cytosolic repressor of Nrf2, since induction of ARE genes require presence of functional Nrf2 and its translocation from cytosol to nucleus.
Induction of ARE dependent genes plays an important role in protection of cells against oxidative damage.
In the present study, we showed that pretreatment of GSH could block the induction of ARE transcriptional activity by 4-HNE, suggesting that 4-HNE may activate NRF2 via depletion of GSH.
Similar(57)
Induction of MTH is recommended to be started as soon as possible by the ERC guidelines.
Induction of ROS is found to be multilateral.
Approaches towards the induction of tolerance are described.
Earlier work shows that the cytoplasmic Ca2+ concentration and induction of apoptosis are directly related to each other48,49,50.
No previous studies with information about parity, augmentation, or induction of labor are available.
The mechanisms controlling induction of proliferation are not understood.
Cell cycle alterations were evaluated by FACS, and the induction of apoptosis was evaluated using the TUNEL assay.
When we examined SI, CYP2B10 expression was absent in hUGT1/Car−/− mice, but induction of UGT1A1 was observed (Fig. 3B).
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