Importantly, we found a good agreement in terms of approximate fold induction between array and RT-qPCR data in general, and especially for IFN-inducible genes, genes involved in lipid metabolism, and five other genes (Additional File 1).
We have developed a computational algorithm for joint inversion of array induction and galvanic data in 2D models.
We have developed a finite-difference (FD) method to model the response of a multiple-spacing triaxial array induction tool with a multiple-electrode type sleeve.
The algorithm simultaneously honors a set of multi-physics data: (a) Pressure-transient, flowline fractional flow, and salt production rate measurements as a function of time acquired with a wireline-conveyed, dual-packer formation tester, and (b) borehole array induction measurements.
The correlation between the Log2 (induction) in the array compared with the Log2 (induction) in the qPCR experiment was 0.944 (Figure 2B).
Oxysterols, intermediates or end products in the metabolic pathway of cholesterol, are endogenous LXR agonists and promote the induction of an array of key proteins, among which are the efflux receptors ABCA1 and ABCG1 [57] [57].
These PRRs trigger distinct signal transduction pathways that culminate in induction of an array of cytokines and other mediators required for host defense.
Heat shock response (HSR), defined as sum total of cellular high temperature-related defense activities, is induced upon exposure to HT. Induction of an array of ubiquitous and evolutionary-conserved proteins known as heat shock proteins (Hsps) is one of the main constituents of the HSR [ 2].
For confirmation of MMP7 induction, predicted by both array analysis approaches, an additional independent cohort from the ERCB-KFB was analyzed (DN, n = 16; controls, n = 9).
To try and discern the pathways involved in cell death induction by BN108, expression array analysis (Methods S1) was performed with RNAs isolated from BT474 cells prior to and after a 4 hour treatment with BN108.
