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The above SAR data demonstrate that electronic parameters influence GSH induction activity.
These results indicate that ACSs possess a chondrogenic induction activity that promotes BMSC differentiation.
Interestingly, however, the induction activity of the synthetic peptide was higher in gilthead seabream than in rainbow trout macrophages.
This fraction yielding the target compound as a single spot on TLC (n-BuOH 25% n-BuOH 25:acetone 4:5:2) showed clear sporulation induction activity.
Our structure activity relationships data show that dithiolethione electronic properties, given as Hammett σp constants, influence glutathione induction activity and compound toxicity.
As SLs also show activity by inducing seed germination of root parasitic plants, the induction activity of these derivatives was also evaluated.
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In this report, we describe the synthesis and GSH induction activities of additional substituted DTTs.
Among the lycoricidine derivatives, compounds L1 and L3 showed relatively higher induction activities on systemic leaves.
The greater induction activities associated with these stilbenoids serve as a useful starting point for the design of improved chemopreventive agents.
Moreover, the quest of new synthetic β-ionone-based compounds possessing anti-proliferative, anti-metastatic and apoptosis induction activities may enable the discovery of compounds which can be used in combination regimes thus overcoming tumor resistance to conventional anticancer agents.
Two series of glycide esters of short fatty acids, designed for avoiding intramolecular transesterification, were prepared and tested for in vitro erythroid differentiation induction activities using the K562 cell line as experimental system.
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