Sentence examples for induces feedback from inspiring English sources

Inhibition of mTORC1 induces feedback Akt activation, which decreased the anticancer efficacy.

A previous study has pointed out that caspase-9 induces feedback apoptosis of the mitochondrion by the cleavage of antiapoptotic Bcl-2 and Bcl-xL.

Similarly, use of NVP-BEZ235 in breast and RCC cells induces feedback regulations to sustain cell survival via ERK- and the FoxO/mTORC2-dependent pathways, respectively [ 85, 86].

Inhibition of the PI3K signaling pathway induces feedback upregulation of extracellular signal-regulated kinase (ERK) and subsequent increased activation of ETS1 as an ERK-related transcription factor.

Inhibition of the PI3K signaling pathway induces feedback upregulation of ERK and subsequent increased activation of the ERK-related transcription factor ETS1. ETS1 is a negative regulator of BRCA1/2 expression, and elevated ETS1 suppresses BRCA1/2 expression.

Climate change is shifting the phenological cycles of plants1, thereby altering the functioning of ecosystems, which in turn induces feedbacks to the climate system2.

Remember, thick strings can be louder than thin strings so are more likely to induce feedback.

Long-term application of RAD001 may, therefore, induce feedback activation of Akt via mTORC2 signalling.

First, the drugs could induce feedback inhibition to the endogenous synthesis of retinoic acid in the target tissues.

Estrogens induce feedback inhibition of LH secretion in patients with an intact hypothalamic-pituitary axis, resulting in decreased testosterone production.

Furthermore, another MEK inhibition-induced feedback mechanism was identified in the MDA-MB231 cell line which led to the activation of 4E-BP1 independently of PI3K-AKT.