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MgSO4 induces a wave of apoptotic neurodegeneration in the neonatal mouse brain, in part defined by activation of caspase-3, an effector caspase in many types of neuronal apoptosis.
Typically, ligand-binding to a cell surface receptor induces a wave of tyrosine phosphorylation (autophosphorylation in the case of receptor tyrosine kinases, or phosphorylation by receptor-associated kinases if the receptor itself lacks catalytic activity) resulting in the generation of phosphotyrosine binding sites for adaptor proteins such as growth factor receptor-bound protein 2 (GRB2).
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This publishing mini-flurry induced a wave of media attention, not all of it positive.
Reaeration induced a wave of transcription, which peaked at 24 hours with 370 genes induced at least two-fold (Figure 2A, Table 1 and Table S1).
In a separate experiment, we induced a wave of cargo at the Golgi using the temperature-sensitive form of VSVG.
Pax6+/- cultures injured in the presence of 10 ng/ml EGF induced a wave of Ca2+ of greater intensity than in control Pax6+/- cultures, which was comparable to the control Pax6+/+ response.
Ghrelin induces a first "wave" of c-Src activation via G protein-dependent signaling that it is followed by a second wave of c-Src activation via β-arrestins-mediated signaling [6].
We recently reported that single dose radiotherapy induces a rapid wave of endothelial cell apoptosis in radioresponsive tissues, such as the gastrointestinal tract and tumors, that acts in concert with direct damage to tissue-specific stem cells to determine organ fate[5], [6], [7], [8].
Repeated γ-irradiation induces a massive wave of apoptosis in the hematopoietic compartment that is dependent on the TP53 target, PUMA.
KDEL-R trafficking can be induced by a wave of cargo or by SRC activation (Bard et al., 2003; Pulvirenti et al., 2008).
We have found that V600EBraf induces an immediate wave of Mek/Erk-dependent proliferation within intestinal crypts.
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