Sentence examples for inducers of differentiation from inspiring English sources

Many studies have made substantial contributions to the differentiation of ESCs into hepatocytes by continuously improving inducers of differentiation and optimizing their combinations and sequences (Li et al., 2010b; Liu et al., 2010b; Wang et al., 2012; Zhang et al., 2013b).

The 'replacement subtype' H1.0 was initially described in highly differentiated, non-dividing cells [9] and expression of its gene can be turned on by inducers of differentiation (reviewed by Zlatanova and Doenecke [24]).

In order to examine if BMP-induced differentiation of hES cells is affected by FGF2 and TGFβ1 present in the culture medium, we planned to test whether depletion of FGF2 and TGFβ1 would affect the percentage, speed or amount of differentiation to a particular fate in our culture conditions, using BMPs as inducers of differentiation.

The hybrid polar compounds (HPCs) are potent inducers of differentiation of murine erythroleukemia cells and a various other cancer cells (Andreeff et al. 1992; Mai et al. 2005).

Of course, also a combination therapy of the cell-penetrating peptides with inducers of differentiation like vitamin D3 and/or valproic acid is possible.

These data suggest that Brk and involucrin may be coregulated and that inducers of differentiation such as vitamin D3 could be considered potential therapeutic strategies.

It was reported that smooth muscle and endothelial cell enriched migration/differentiation-associated lncRNA (SENCR) and myocardin-induced smooth muscle lncRNA, inducer of differentiation (MYOSLID) lncRNAs control the phenotypic switching of VSMCs to maintain their contractile phenotype18,19.

Hexamethylene bisacetamide (HMBA) is a hybrid bipolar compound that is a potent inducer of differentiation of various transformed cells and induces apoptosis70,71.

IFN-γ, IFN-α, and IL-12 induce Th1 differentiation, IL-4 is the primary inducer of differentiation into Th2 cells, and combinations of IL-1, TGF-β, and IL-6 induce Th17 differentiation.

The scramble group did not differentiate into adipocytes in the presence of the minimal inducer of differentiation, with mock, insulin, or dexamethasone treatment, whereas in the absence of the inducer, the si Creb3l4 group exposed to mock treatment differentiated partially (Supplementary Figure S3b).

PMA, an inducer of differentiation of monocyte to macrophage, enhanced the expression of hres in U937 cells, as also reported earlier [10].