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In the present study, we used menthol (50 µg/kg, i.v ., an agonist of the TRP melastatin-8 (TRPM8) channel ("cold receptor"), to induce warmth-seeking behavior and resiniferatoxin (RTX, 0.5 µg/kg, i.v ., an agonist of the TRP vanilloid-1 (TRPV1) channel ("warmth receptor"), to induce cold-seeking behavior.
(Two emoticons per email induced the greatest warmth in the recipient, Yoo found).
Little green sprouts poking through soil, reaching for the April sun in the glass-induced warmth on an otherwise chilly midday.
I stayed in a painkiller-induced warmth for the first week of recovery.
Lesion of no structure affected cold-seeking behavior induced by heat exposure or by pharmacological stimulation of the transient receptor potential (TRP) vanilloid-1 channel ("warmth receptor").
Capsaicin pretreatment induced profound loss of warmth and heat pain sensitivity (pain threshold and supra-threshold ratings) as assessed by quantitative sensory testing, indicative of efficient TRPV1-fiber defunctionalization (all outcomes: P < 0.0001).
The wind makes the man to cling more tightly to his garment, while the sun's warmth induces him to take it off.
Temperature of the grills was maintained at 40.0°C (± 0.3°C) and induced a perception of gentle warmth.
The non-noxious stimulation induced a gentle sensation of warmth and the noxious stimulation induced a perception of heat pain (visual analogue scores of 0 and 46 mm, respectively).
They are also contrary to the finding that lesioning the POA attenuates LPS-induced warmth-seeking behavior in toads [12].
With the exception of one study in toads [12], the neuronal circuitry of LPS-induced warmth-seeking behavior has not been investigated, and nothing is known about brain mediation of LPS-induced cold-seeking behavior.
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