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LTP that is induced solely by electrical afferent stimulation (electrically induced plasticity) was first reported roughly 40 years ago in the DG of the rabbit after high-frequency stimulation (HFS) of the perforant path (Bliss and Lomo 1973).
Pinacidil inhibited Ca2+ loading induced solely by in vitro conditions, but was not as efficient on DNP-induced Ca2+ loading.
Reversible transition of self-assembly and disassembly for PS720-P2VP200-PEO375 multinompaqueous micellesolutioneous solutinduceduced solely by changing temperature has been investigated.
Increases in the degree of fiber alignment induced solely by extrusion (0.08 0.25) or compaction (0.25 0.44) were not as great as those by the combination of extrusion and compaction (0.35 0.45).
Surprisingly, in the absence of any external loading, the hoop stress induced solely by the surface effects is identical to that in the corresponding case in a linearly elastic solid.
To determine if radiation induced effects were additive to the DNA damage induced solely by GNPs the percentage variation in DNA damage induced by GNPs was compared to the percentage increase in DNA damage caused by GNPs and irradiation as in Figure 3A.
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Also phosphatidylserine externalization, augmentation in the level of caspase-3, PARP, BAD, Apaf1 and cleaved caspase-9 along with decreased expression of Bcl2 and release of cytochrome c confirmed that, Cd2+ dose dependently induces solely intrinsic pathway of apoptosis in SK-RC-45, independent of JNK.
Natural uranium induces chemical toxicity, especially nephrotoxicity, which is more harmful than radiotoxicity; whereas radium and radon are thought to induce solely radiotoxicity (Wrenn et al. 1985).
This suggests that the tested pro-senescence kinases, although strongly inducing transcription of SASP-component and other pro-senescence regulator genes via NF-κB transcription factors, do not induce senescence solely through the NF-κB pathway.
However, it is important to realize that DNA reactivity (e.g. DNA adducts) does not necessarily correlate with mutagenicity, and chemicals that can react with DNA may not necessarily induce tumors solely as a result of direct interaction with DNA (Swenberg, et al., 2008).
However, in most of these inducible models, IL-17 response was solely induced without the confounding interaction with other T cell cytokines, such as IFN-γ and IL-13.
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