If both vessels are located parallel to each other, dilation of the host tissue vessels (and not of the tumour vasculature) may induce a redirection of blood flow in favour of the surrounding normal tissue ('steal' phenomenon).
Condition 3 ensures that the wireless traffic induced by the redirection mechanism is lower than that required when it is not applied.
The results of this study support our hypothesis regarding uncoupling-induced redirection of carbon flux into glycolysis and lactate production, and suggest mitochondrial proton translocation as a potential target for controlling adipocyte lipid metabolism.
Together with the observed levels of sugars, organic and amino acids, which were, on an average, significantly higher in acclimated plants of Rsch, this points to a differential cold-induced redirection of carbon equivalents in both accessions.
As this redirection is rapidly induced by enzyme oxidation, post-translational modifications and metabolic feedback loops, it facilitates an immediate protection of the oxidant-exposed cell [ 13, 18].
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At least two fundamental changes in tumor metabolism are induced by DCA that antagonize tumor growth, metastases and survival: the first is the redirection of glucose metabolism from glycolysis to oxidation (reversal of the Warburg effect), leading to inhibition of proliferation and induction of caspase-mediated apoptosis.
No changes related to the upper part of glycolysis were observed in the current study, although it is clear that the need for compatible solutes leads to a redirection of a part of the carbon source to alleviate the stress induced by increased osmolarity.
Installation of the deflector resulted in a redirection of the fluid flow from the returning turbine blade, therefore reducing the negative torque induced on the system.
Following proteomic analyses, the glycolytic enzymes Pgi1p, Fba1p, Tdh3p, Gpm1p, Eno1p and Cdc19p were identified to be strongly induced, while TCA cycle proteins Aco1p, Fum1p and Mdh1p show very low abundance in hypoxic conditions, pointing at a redirection of the central carbon metabolism towards fermentation.
A rapid redirection of isoprenoid biosynthesis from sterol derivatives toward sesquiterpenoid phytoalexins was found in plants of the Solanaceae family when wounded tissues were exposed to elicitors or fungal pathogens which induced a hypersensitive response [36],[36].
