Sentence examples for induced imbalance from inspiring English sources

Elevation in these reactive substances induced imbalance between TAC and production of free radicals leading to lipid peroxidation [ 15].

Moreover, the AS-BMSCs induced imbalance in the ratio of CCR4+CCR6+ Th/Treg cells by reducing Treg/PBMCs and increasing CCR4+CCR6+ Th/PBMCs, and also reduced Fox-P3+ cells when co-cultured with PBMCs.

Wilde et al. [ 12] summarizes one mechanism that involves the potential of alcohol use to alter pathophysiologic responses to injury through a traumatically induced imbalance of neurotransmitter action which may increase excitotoxic reaction.

This review summarizes an updated account of available information on heavy metals induced imbalance in the redox systems in the body and their clinical and pathophysiological implications as well as use of certain natural and synthetic products to mitigate their toxicity.

While in vivo apoptosis does not require a death receptor, such as Fas, recent studies have demonstrated that apoptosis is linked to an induced imbalance in the members of the Bcl-2 family.

This is similar to what has been observed in autosomal aneuploids and artificially induced imbalances of autosomal genes where dosage differences are also partially compensated [ 29].

Treatment of L. donovani parasites with Compound 1 inhibits LdTR activity, induces imbalance in redox homeostasis by enhancing ROS, disrupts the mitochondrial membrane potential, modifies actin polymerization and alters the surface topology and architecture.

Below we discuss these data with reference to possible functions of PrPC in cellular iron metabolism, and the implications thereof in inducing imbalance in iron homeostasis observed in prion disease affected brains [15], [16], [45].

Since iron is required for essential metabolic processes and is also potentially toxic if mismanaged, these results suggest that loss of normal function of PrP due to aggregation to the PrPSc form induces imbalance of brain iron homeostasis, resulting in disease associated neurotoxicity.

High-performance liquid chromatography analysis demonstrated that mild folate depletion (100 nM) sufficed to induce imbalance in both the nucleotide and AdoMet pools in all prostate cell lines.

Tobacco is a rich source of multiple pro-oxidants with oxidative stress thought to have a major role in inducing imbalance in innate cell homeostasis in COPD.