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Sherman, W., Beard, H. S. & Farid, R. Use of an Induced Fit Receptor Structure in Virtual Screening.
Aspeslagh, S. et al. Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis.
A two-step induced fit mechanism involving binding and subsequent domain rearrangement is proposed.
This lock and key nature causes enhanced induced fit in pemafibrate-ligated PPARα.
The structures reveal that the non-canonical PAMs are recognized by an induced fit mechanism.
Collaborating with other scientists, he observed that enzymes can change their shape as they interact with different molecules, an effect they termed "induced fit".
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The organizational adaptation that occurs between the ivory tower and corporation is called 'corporate-induced fit'.
Picaud, S. et al. 9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain.
All docking calculations were performed using induced-fit-docking module of Schrödinger suite [13].
This circumstance again emphasizes the ability of aldose reductase to react with induced-fit behavior upon ligand binding.
Regarding the sampling aspect, protein flexibility could be partially considered by using ensemble docking or induced-fit docking strategies.
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