Thus, previous work in TPA-induced differentiating myeloid leukemic cells has demonstrated a strong induction of these matrix metalloproteases [ 14] which is in accordance with differentiating pMTH1 U937 cells and in contrast to the asCD11b transfectants.
p21Waf1/Cip1 upregulation in PMA-induced differentiating U937 cells, it can be assumed that WIN 55, 212-2 transmitted cell cycle arrest signals, which are dependent on PKC-activation and probably on the cell type and its proliferative state.
Subsequently, we examined whether adipogenic, osteogenic, or chondrogenic differentiation was induced by differentiating agents in these senesced 520d/NHDF cells treated with irradiation (77 days after transfection).
DNA adducts induced in differentiating or stem cell spermatogonia, however, did not persist to spermatozoa.
How is D2 induced in differentiating myoblasts?
Confluent preadipocytes were induced to differentiate using a standard differentiation medium (DM2-L1, Zen-Bio Inc, Research Triangle Park, NC, USA).
In NSPCs induced to differentiate, overexpressing miR-106b~25 enhances differentiation toward the neuronal lineage.
Pluripotent stem cells have an ability to self-renew, yet can also be induced to differentiate into a wide range of differentiated cell types.
NSC cultures were induced to differentiate for 3 weeks in NSC differentiation media.
HUES-9 NSC cultures were induced to differentiate for 3 weeks in neuron differentiation medium.
For example, Muse-AT cells demonstrated formation of lipid droplets when induced to differentiate into adipocytes (Figure 4A), as well as characteristic smooth muscle striations when induced to differentiate into myocytes (Figure 4B) [26].
