This indicates that the three R-MuLV-induced tumour cell lines share a virally encoded or induced antigenic determinant, which activates T-cells.
Considering that hsp65 is a highly conserved protein, we suggested that the anti-Bhsp65 T-cell response observed in naïve conventional F344 rats is induced via determinant mimicry by hsp65-bearing environmental microbial agents in the conventional housing facility.
For virulence experiments, LF82 and mutant derivates were cultured without agitation in order to induce virulence determinants [17].
An incidental point: since these are the sequent formulations of conditions induced by the determinants ⟨T, T, T⟩ and ⟨F, F, F⟩ one might think of them together as expressing idempotence and therefore as being interchangeable with the simpler pair φ ≻ φ Knot φ and φ Knot φ ≻ φ.
Extreme parity, a previous history of preterm birth or abortion, younger maternal age, inadequacy of prenatal care, reported hypertension, antepartum hemorrhage, premature rupture of fetal membranes and induced labor are significant determinants of preterm birth [ 4- 6].
This highly unusual empirical finding can be interpreted as an increase in accessibility of an epitope to its ligand due to conformational changes in the target determinant molecule induced by binding of a paired "stimulatory" ligand to its adjacent epitope.
Our data indicate that expression of the nickel resistance determinant is induced by nickel.
Subsequently, protein sequences were predicted and then analyzed using Blastp and Blast/CDD and hits were found for conjugal transfer proteins (traA, traC, traD and traG/VirD4), inner membrane protein, partitioning protein ParA, resolvase, putative stability determinant, filamentation induced by cAMP (Fic), helicase/methyltransferase and hypothetical proteins.
Thus far, in summary, there appear to be two major determinants of the folding patterns of the TA domain peptides of the p53 family: nucleation largely by hydrophobic interactions (a kinetic determinant) and stability induced by ion-pairs or long range electrostatics (thermodynamic determinants).
Although this study was not designed to explore these mechanisms, the significant correlation between urinary output and renal artery blood flow, APP, and renal filtration gradient suggests that the decreases in these variables induced by IAH were major determinants of oliguria.
