Overall, these data showed that HPVs induced coordinated changes in KC gene expression, detectable in unstimulated 'baseline' cells (mainly expression clusters 1, 5, majority of cluster 4) or after poly(I C) stimulation (mainly expression clusters 2, 3, 6).
Hierarchical clustering of 320 differentially expressed genes further demonstrated that mCRP and pCRP treatment differentially induced coordinate programmatic gene expression and differentiation (Fig. 3b).
Here we used tree ring data from over 3000 trees – representing 26 populations of 16 common European tree species sampled at six locations that span more than 20° in latitude – to test whether drought induces coordinated changes in carbon isotope ratios and stem basal area increments (BAI).
Here we provide the first comprehensive test of whether drought induces coordinated changes in carbon isotope ratios and stem growth rates across Europe's dominant tree species and main forest types, an assumption which is routinely made in the literature but has yet to be rigorously tested.
In conclusion, interference with RA transport at RARα into the nucleus is sufficient to induce coordinated, heritable, chromatin repression at multiple loci of a RA-responsive gene network downstream of RARα, with pleiotropic biological outcomes.
Indeed, the presentation of olfactory cues has been shown to induce coordinated motor behaviour of rat pups as young as P3 [62], considerably earlier than when similar movements can be observed in free-moving conditions.
A maternal HF diet prior to conception, during pregnancy and lactation induces coordinated and long-lasting changes in expression of Igf2 and key fat metabolic genes and miRNAs in the offspring, which may have long-term effects on their health.
To date, 44 CT gene families have been identified; however, the protein products of only three gene families have been found to induce coordinated humoral and cellular responses, including NY-ESO-1, MAGE-A, and SSX antigens (Scanlan et al, 2004).
IFN-γ repressed genes by suppressing the function of enhancers enriched for binding by transcription factor MAF. Mechanistically, IFN-γ disassembled a subset of enhancers by inducing coordinate suppression of binding by MAF, lineage-determining transcription factors, and chromatin accessibility.
Implanted and spontaneously arising tumors induce coordinate growth of blood and lymphatic vessel triads.
These slowly growing benign tumors thus also induce coordinate growth of large vessel triads, with the arteries particularly enlarged relative to the veins and lymphatics.
