Sentence examples for induced by substituting from inspiring English sources

The mutant of moesin was induced by substituting threonine at 558 amino acid residues with Ala (pcDNA3/HA-moesinT558A pcDNA3/HA-moesinT558A or with asp (pcDNA3/HA-moesinhibitedas activated mutant, respectively.

Furthermore, in the absence of a consideration of possible protein conformational changes induced by substituting alanines in the active polyubiquitin binding sites of angiocidin, these results also suggest that residues I290 M294 play a more important role than residues L216 L220 in the binding of polyubiquitin and the induction of endothelial cell apoptosis.

This vibrating peak is attributed to the local vibrational mode (LVM) induced by P dopants substituting O atoms [26].

To eliminate species specific responses we have utilised two different haematopoetic cell lines, 70Z/3 mouse pre-B-cells and human HL60 promyelocytic leukaemia cells, to study the mechanism of apoptosis induced by N-substituted benzamides.

This can be rationalized by the smaller change in the electrostatic energy landscape induced by the −NH2 substituted SAM in the region of the −CN substituted molecules (cf. 4).

Constitutive expression of Tfcp2l1 at levels similar to those induced by LIF effectively substituted for LIF or Stat3 in sustaining clonal self-renewal and pluripotency.

In conclusion, the demonstration that at a dose of 50 mg kg−1, DMXAA demonstrates excellent antitumour activity in TNFR1−/− mice without host toxicity suggests that other cytokines or vasoactive agents are induced by DMXAA and can substitute for TNF.

In contrast, the attenuation of the 2fly- and trypsin-induced relaxations induced by ChTx was not reproduced by substituting IbTx for ChTx.

A novel multi-target antibody to morphine and derivatives was induced by designed morphine-3-site substituted and the polyclonal antibody was prepared with immunizing rabbits.

The cracking and durability problems induced by concrete brittleness can be effectively avoided by substituting concrete with ECC.

To delineate the mechanism underlying disulfide bond-mediated p62 polymerization induced by Nt-Arg, each Cys residue was substituted to alanine (Ala).