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It is notable that the mRNAs for enzymes for proline degradation were induced before, not after, the switch to high-proline medium: clearly they are not induced by the presence of substrate.
The timing of randomization, therefore, is more important than in a patient setting: it needs to be assessed whether the disease was induced before actual randomization and whether the order of inducement was randomly allocated.
Expression of miR-203 was either never induced (mimicking cells lacking miR-203), induced before intravenous injection (day 0, phenocopying constitutive miR-203 expression), or induced 10 (dormancy phase of engrafted cells), 29 (establishment of micrometastases), or 56 days (macrometastatic colonization) after injection.
Birth should not be induced before 39 weeks of gestation, according to the guidelines.
TCF1 expression is induced before the ChILP stage.
Specific cytotoxic T-lymphocytes need to be induced before hybrid cell application in clinical studies.
Compared to our study, AD treatment was induced before androgen-sensitive tumour cells were injected subcutaneously and thus before solid tumours were developed.
Here, we use single-cell fluorescence imaging to show that an all-or-none switch is induced before lipid accumulation occurs.
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When differentiation was induce before the cells had reached confluence, cells were less differentiated than under "classical conditions" and C/EBP-α was expressed at low level, that did not allowed quantification.
Under -/- conditions, RFP is expression is induced as before; However, observe that P lac promoter induces expression of cI to shut down expression of GFP (see Figure 7d).
Structural damage could be localized through comparing the quasi-static moving load induced response before (taken as baseline) and after damage.
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