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Thus, although CES3 mRNA expression was apparently induced and might be a compensatory mechanism following knockdown of CES1 expression, it does not appear to be induced at the active enzyme level because CES3 also has a predicted molecular weight of 60 kDa.
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However, the warm glow induced at the multiplex fades.
Furthermore, FAPα is also induced at regions of active tissue remodelling during mouse embryogenesis, including somites and perichondrial mesenchyme from cartilage primordia [ 35].
An activator molecule can be bound to an allosteric site and induce a reaction at the active site by changing its shape to fit a substrate that could not induce the change by itself.
Moreover, when Gaudí fish were induced at 10 dpf, the number of active RSCs had increased to 113.1±7.4 (Fig. 8B-E).
At the nuclear level, the activation of VDR induces heterodimerization between the active VDR and the retinoic receptor (RXR).
We used a single-chain antibody that selectively binds to Ligand Induced Binding Sites (LIBS) at the active conformation of the glycoprotein IIb/IIIa receptor and induces strong adherence to activated platelets in the presence of fibrinogen.
CK1δ transcription variants induced at 15°C for 14 h are more active and incorporate more radioactive phosphate in the substrate than CK1δ transcription variants induced at 37°C for 2 h (Fig. 3a).
The analysis of Gaudí fish induced at a pre-neurogenic retinal stage revealed the presence of 60±4.5 active RSCs.
The highest ratios and numbers of cytokine genes are induced in the early, active infective state, in which C. trachomatis is at the beginning of the replication cycle and metabolically active (4 h).
Two Mn2+ ions bind at the active site, inducing relocation of the scissile phosphodiester towards the active site (1.6-Å shift in the position of the P atom; Figure 3B).
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