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Chu and colleagues reported that CD40 ligation on CLL B cells induced a programme of events in which shifts in the balance of anti-apoptotic and pro-apoptotic FLIP and FADD were associated with initial resistance to Fas-mediated killing followed by subsequent sensitization.
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Hypoxia is a common feature of human cancers, which induces a transcription programme mediated mainly by hypoxia-inducible factor-1 α (HIF-1 α) that promotes aggressive tumour phenotype (Harris, 2002; Vaupel and Mayer, 2007; Bristow and Hill, 2008).
Thus, our results indicate that sustained gastrin signalling induces a transcriptional programme that differs significantly from the transcriptional response to transient gastrin signalling.
Thus NFAT signalling in tumour cells induces a transcriptional programme of genes that includes factors that promote invasive migration leading to metastatic dissemination.
Taken together, these data strongly suggests that endogenous STAT3 does indeed become activated and induces a transcriptional programme that may modulate the levels of I/R-cell death in cardiac cells.
The latter induced a brown-like genetic programme, suggesting that a secreted molecule from the muscle cells was responsible for inducing browning of WAT.
First, Boström and colleagues identified that muscle-specific overexpression of PGC-1α induced a brown-like adipose tissue gene programme.
The expectation had induced a torpor.
Uehara induced a groundout.
This mixed response suggests that activated TILs induce a complex transcriptional programme in MSC that induces individual cells to produce functionally divergent effects.
Macrophages of the M1 type induce a pro-inflammatory programme that can inhibit tumour growth by inducing the recognition of tumour cells by the immune system.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com