Dietary supplementation with inorganic nitrate (NO3−) has been shown to induce a multitude of advantageous cardiovascular and metabolic responses during rest and exercise.
Many GPCRs are known to couple to more than one G protein subtype and induce a multitude of signaling pathways, although the in vivo relevance of particular pathways is mostly unrecognized.
NAC has been shown to induce a multitude of molecular changes related to tumorigenesis [ 4].
Activation of TLR-4 induces a multitude of pro-inflammatory cytokines via activation of transcription factors, nuclear factor (NF κ B[ 18].
CNT induce a multitude of genotoxic responses including DNA strand breakage, oxidation, micronuclei induction, chromosomal aberrations, formation of γH2AX foci, and mutant frequencies [ 132].
In addition, it has been suggested that during transformation PML RAR α induces a multitude of alterations in the chromatin architecture.
The signalling capacity of the transactivated EGFR is not restricted to coupling GPCRs to the Ras-MAPK pathway, but rather functions as a critical intermediate for Gq-, Gi-and G12/13-coupled receptors to induce a multitude of biological responses.
Symbiotic microorganisms have been found in almost all arthropod lineages, where they can induce a multitude of different phenotypes, including, for example, defense against pathogens and changing of host sex ratios and behavior (Buchner 1965; Moran et al. 2008).
Chromosomal rearrangements induce a multitude of genomic variations such as duplications, deletions, inversions, and translocations, leading to the gain or loss of genomic material [ 32, 33] and are observed in both sexual and asexual fungi [ 31, 34] (Fig. 2C).
Both the flagellin protein and synthetic peptides derived from the flagellin N-terminus are recognized by most plants and can induce a multitude of defense responses including: accumulation of reactive oxygen species (ROS), induction of defense genes, and cell wall reinforcement by callose deposition.
