In addition, having a porous network with small porosity value induces a limit on threshold capillary number, i.e., the smaller the porosity, the greater should be the Ca to acquire a full percolating system.
Because of high surface-to-volume and the magnetic interaction, bare IONPs tended to aggregate and lower magnetic responds by oxidation, which induce a limited drug targeting [13].
PIs can only induce a limited apoptosis in MPM cells most likely due to their inability to activate PFM and to cleave Mcl-1 protein [ 24].
Macian et al. [ 74] reported that Ca2+ signaling using the calcium ionophore ionomycin could induce a limited set of anergy-associated genes in a NF-AT dependent manner to render T cells tolerant of antigen.
Most previous anti-CD4 therapeutics have been associated with increased incidence of rash, and in this study MTRX1011A also induced a dose-limiting moderate pruritic rash [ 15, 17, 20].
Compared to innate immunity, incorporation of adaptive immunity induced a further stabilized limit cycles, bifurcation from the equilibrium.
13 While animal model data have shown that epothilones induce a dose-limiting neurotoxicity and recovery after withdrawal of treatment, 14 there is no longitudinal pathological human data to confirm this finding.
Fourth, we excluded 163 cases a posteriori that differed from the included cases; this may have induced a selection bias, which may limit the external validity of our study.
The limiting flux induces a performance limitation of ultrafiltration systems, the understanding of this phenomenon and the ability to predict the limiting flux are essential for improving the design and operation of ultrafiltration processes.
However, even if they exist, their relevance was limited and should have induced a negligible bias.
