Exact(2)
Gravitational waves can induce transformations on the state of phonons that can be observed through quantum state discrimination techniques.
As with all types of cancer, PCa is the result of genetic and epigenetic alterations that induce transformations of normal glandular epithelia [ 4].
Similar(57)
The Wnt/β-catenin signaling pathway can induce transformation of mesenchymal stem cells to alveolar epithelial cells [35].
Apart from the brain, deregulation of Hh, Notch and Bmi pathways has been proposed to induce transformation of mammary stem cells [65].
However an increase of kit signaling is not per se able to induce transformation of these cells and to sustain melanoma development [36] [37].
These data indicate that wild-type BRAF would be unlikely to induce transformation.
Oncogenic viruses can induce transformation via expression of only a small number of viral genes.
Likewise, over-expression of the wild-type MLK3 was shown to induce transformation of NIH3T3 fibroblasts (12).
However, overexpression of Aurora-A/STK15 in primary MEFs does not induce transformation [ 22] suggesting that additional mutations/alterations are required.
In T. parva and T. annulata, the macroschizont life cycle can induce transformation of the infected cell [ 46].
Notably, overexpression of Akt1 alone is insufficient to induce transformation, although expression of activated Akt does accelerate tumor development [ 13].
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