Binding of Aβ peptides to the plasma membrane was sufficient to induce trafficking inhibition where peptides with reduced plasma membrane binding and internalization had lesser effect on mitochondrial motility.
Notably, jervine, a close chemical relative of cyclopamine, was also able to induce trafficking of Smo to the primary cilium (Fig. 1A, 1C).
The combination of both responses could induce trafficking failure.
An alternative possibility proposed by many groups (Filtz et al., 1993; Ng et al., 1997; Starr et al., 1995; Zhang et al., 1994) is that D2 agonists induce trafficking of D2L receptors preferentially retained in intracellular storage.
Environmental engineers call this phenomenon "induced traffic".
But TrafficGauge points out that its customers have the luxury of listening to music or silence rather than stress-inducing traffic reports.
This approach eventually makes the original problem worse, by generating what transportation planners call "induced traffic": every mile of new highway lures passengers from public transit and other more efficient modes of travel, and makes it possible for residential and commercial development to spread even farther from urban centers.
The only point most studies agree on is that HSR connections generate induced traffic due to the decreased generalized cost of transportation created by increased access.
Deletion or alteration of this motif induced trafficking impairment in both in vitro systems and animal models, the latter one accompanied by photoreceptor cell death, displaying its very important role for transport to the membranous rod outer segment (ROS) [14] [16].
Perhexiline induces trafficking of HER3 to lysosome.
Similar differences in Dx- and Su(dx -induced trafficking of N were observedx -inducedmaginal discs.
