Sentence examples for induce substantial changes from inspiring English sources
Administration of the D2 agonist quinpirole (10 μM; n=3) failed to induce substantial changes in EPSP amplitude (8.5±1.3 mV compared to 6.4±1.2 mV) (Table 1).
In Sweden, the goal to replace fossil fuels could induce substantial changes in the current management and use of forests.
This conclusion is also supported by computational studies, which indicate that construction of the EERE chimera did not induce substantial changes in the structure of EcoRI.
Variations in fluid flow rates from below may induce substantial changes in the temperature and composition of fumarolic gases, which may be eventually accompanied by changes in the volume and morphology of the coexisting lake (e.g., Rouwet and Tassi 2011; Christenson et al. 2015; Hurst et al. 2015).
It is, however, possible that a further decrease in pH, particularly in the range near the pKa of carboxylates (4 4.5) may induce substantial changes in the RKIP pocket structure and its ligand-binding properties.
The fact that in our model recombination has only a weak effect on virus load, however, is compatible with strong selective pressures on escape mutants, as observed experimentally [23], [43] [47], because large changes in viral fitness in vivo do not necessarily induce substantial changes in virus load [48], [49].
We found that focal electrical stimulation of cortical neurons induced substantial changes in the response magnitude, response latency and receptive field of ipsilateral cochlear nucleus neurons.
Basal LXRα overexpression induced substantial changes in genes relating to metabolism (Fig 4A).
In a similar study the application of the fungicide enostroburin induced substantial changes in bacterial community in wheat phyllosphere [ 18].
In general, ligand binding induces substantial changes in the active site electrostatic microenvironments for all four positions where the SCN probe was incorporated.
Previous studies by Gu et al. [ 18] showed that the application of the fungicide enostroburin induced substantial changes in the bacterial community.
