Sentence examples for induce sensitivity from inspiring English sources

Together, these data suggest that expression of the GRP and V1A receptors induce a more transformed phenotype in CHO cells and induce sensitivity to substance-P analogue-induced growth inhibition.

We hypothesized that artificial overexpression of HER2 in TNBC cells might induce sensitivity to anti-HER2 agents in these cells.

Therefore, down regulation of expression of these genes may reverse the resistance to selenium and induce sensitivity to selenium treatment in cells (i.e. cell death would be observed).

The E3 ubiquitin ligase from Pseudomonas syringae has been shown to induce sensitivity in tomato plants by targeting a host kinase, Fen, to the proteasome, which leads to the inhibition of the Fen-activated immunity-associated programmed cell death [35].

The hypothesis that chemotherapy may induce sensitivity to endocrine agents is also intriguing.

Velcade is mainly used in multiple myeloma as a means to overcome resistance and induce sensitivity when used in combination with a variety of other chemotherapeutic agents.

Bacteria cause disease by secreting or excreting toxins (as in botulism), by producing toxins internally, which are released when the bacteria disintegrate (as in typhoid), or by inducing sensitivity to their antigenic properties (as in tuberculosis).

Binding of ligands activates Notch by inducing sensitivity to metalloprotease cleavage at site S2, which lies about 12 13 amino acids external to the transmembrane domain [14], [15].

In HCC1937 cells, restoring BRCA1 abrogated sensitivity to apoptosis in the presence of DNA-damaging agents, including cisplatin and etoposide, while inducing sensitivity to the antimicrotubule agents paclitaxel and vinorelbine, suggesting that BRCA1 acts as a differential modulator of apoptosis depending on the nature of the cellular insult [31].

We hypothesised that changing prednisolone for dexamethasone (a term we designated 'steroid switch') would be associated with tumour responses and could re-induce sensitivity to abiraterone.

We hypothesized that JAK/STAT negative regulators may lose their tumor suppression function in TKI-resistant AML cells due to epigenetic silencing, and the re-expression of these genes could re-induce sensitivity to CEP-701.