Sentence examples for induce repression from inspiring English sources

p53 binds to several microRNA promoters to induce repression.

In addition, p65 can induce repression of transcription by de-acetylation of histones, through association with histone deacetylase (HDAC).

To stochastically induce repression of the two FLC transgenes, we exposed F1 plants to 4 6 weeks of cold followed by 7 days growth in warm.

From these studies, one can get the conclusion that FOXA1 is needed to permit ER tamoxifen interaction with DNA but is not sufficient to induce repression.

DNA methylation can induce repression of gene transcription, physically preventing transcription factor binding and reducing access to gene regulatory regions [ 11, 12].

Blimp1 together with Prdm14 plays a critical role in early germ cells as they induce repression of the somatic program, initiation of PGC program-coupled epigenetic reprogramming, and re-expression of pluripotency genes (Ohinata et al., 2005; Yamaji et al., 2008).

This occurred even with an inducible system to control the temporal disruption, where cell death occurs immediately upon inducing repression of the system masking the homozygous mutation.

However, overexpression of Cdc6 in mutant Bmi1 cells failed to mediate Arf or Ink4a repression (Fig. 4A,D) demonstrating that CDC6 induced repression of the INK4a/ARF locus is dependent on Polycomb function.

However, under the same conditions PMA had no effect on NRXN3α E20 or NRXN2α splicing at baseline and did not prevent the depolarization induced repression of these exons (Figure 4 panels C1, C2 and D2).

Therefore, to determine whether miRNA induces repression of IRS-1 expression posttranscriptionally, we selected several miRNAs targeting IRS-1 and measured cellular levels of these miRNAs in hepatocytes with dysfunctional mitochondria.

While these results are consistent with the anti-apoptotic effects of PBA in other systems [35], [51], it was surprising that PBA could overcome the apoptotic effects of BFA as PBA has no effect upon the BFA induced repression of APP proteolysis.