Sentence examples for induce off from inspiring English sources

However, siRNAs with an exact sequence identity of ≥17 nt can already induce off target effects [ 25].

But while fluorescent jackets and Perspex goggles are annoying, they don't tend to induce off-the-scale levels of anxiety or deep-rooted feelings of impotence and frustration in me every time I see them.

The latter leads to the release of volatile radiolysis products that may induce off-odors in the polymers, thereby altering the migration characteristics of packaging materials.

CRISPR/Cas9 generally disrupts their intended target sites reliably; however, an important question to consider is to what extent these nucleases induce off-target cleavage events, especially in therapeutic application.

Considering that CRISPR/CAS9 gene editing technology could induce off-target genomic mutations, the Jurkat-KI-R5 cells can be further employed to improve the efficiency and safety of CRISPR/Cas9 mediated disruption of the CCR5 gene.

Previous studies suggested that CRISPR/Cas9 system would probably induce off-target mutations because the binding to genome could tolerate sequence mismatches distal from the PAM at the 5′ end of sgRNAs.

At least in its initial incarnation, the system is less discriminating than users would like, and single-guide RNAs have been shown to induce off-target effects in the human genome.

Since 3-MA treatment may induce off-target effects, we further confirmed that 3-MA treatment was efficient at reducing the number of LC3-positive autophagosomes in TzbR cells.

These suggest that the RGENs can also induce off-target alterations in other organisms.

It is also possible that 4EGI-1 could induce off-target effects as previously reported.

Morpholinos sometimes induce off-target effects, which are caused by upregulation of p53 and subsequent apoptosis.