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Exact(43)
Objective: To assess the ability of peripheral blood serum from women with endometriosis to induce monocyte chemotactic protein-1 (MCP-1) secretion by monocytes and the putative role of the interleukin-1 (IL-1) system in endometriosis-associated monocyte activation.
PF4 can induce monocyte cytokine production [22].
Interestingly, VEGF has also been shown to induce monocyte activation manifested by the induction of monocyte chemotaxis [7].
These data demonstrate that concentrations of PF4 relevant to ECM induce monocyte cytokine production, including IL-6 and TNFα.
Our results showed that LL-37 at the concentration of ≥1.25 µM ≤10 µM can induce monocyte differentiation.
Galectin-3 can act in an autocrine or parcrine fashion to induce monocyte migration [43] or alternative macrophage activation [7] and regulate cytokine expression [44].
Similar(17)
Human primary monocytes were stimulated with CSF-1 for indicated time points to induce monocyte-to-macrophage differentiation.
To induce monocyte-to-macrophage differentiation, the THP-1 cells were cultured for 72 h in the standard culture medium supplemented with 100 nM phorbol 12-myristate 13-acetate (PMA; Sigma-Aldrich, St . Louis MO).
Endothelial-derived microvesicles may be activated under hyperglycemic conditions to induce monocyte-adhesion in other endothelial cells via increased NADPH oxidase activity [ 49].
Granulocyte-macrophage colony-stimulating factor (GM-CSF) and macrophage colony-stimulating factor (M-CSF) induce monocyte-macrophage lineage differentiation both in vivo and in vitro.
In fact, visfatin can induce monocytes to produce proinflammatory cytokines such as IL-1, TNF, and IL-6 [ 64].
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