Sentence examples for induce memory impairment from inspiring English sources

In animal models, systemic administration regimes resembling chronic exposure to this drug (50 mg/kg, twice a day during one week), induce memory impairment.

Anisomycin (a protein synthesis inhibitor) and DL-α amino-adipic aciDL-α amino-adipicglial glutamine synthetase enzyme inhibitor) were microinjecteDL-α amino-adipicn acidr cued fear-conditioning to induce memory impairment.

This result indicates that HA can induce memory impairment.

However, Aβ itself does not induce memory impairment because transgenic experimental mice, who had higher levels of Aβ-40 and −42 display better memory performance than non-Tg mice.

Amyloid alone did not induce memory impairment despite the presence of higher levels of both Aβ-40 and -42 in the transgenic 3-month-old mice (hemizygous + B6 deficient + anti-HA antibody) compared with non-Tg mice [9].

Aβ25-35 wadministeredred by intracerebroventricular (ICV) injection to induce memory impairment.

Severe stress exposure induces memory impairment probably through activating inhibitory modulatory mechanisms such as opioidergic pathways.

HA induced memory impairment in our study and this impairment was greater in the presence of Aβ (Fig. 1), i.e., even if Aβ were to be decreased, HA would still be present in the affected brain tissue.

Our data showed that TL prevented Pb induced memory impairment and AChE dysfunction in a dose-dependent manner, indicated by the in vitro and in vivo studies.

LPS also successfully induced memory impairment in the Y maze test, neuroinflammatory responses, and oxidative stress such as increases in mRNA levels of interleukin (IL -1 β and IL -1 heme oxygenase-1, microglial activation, and iNOS activity in hippocampus [ 28].

The results suggest that neuroinflammatory markers might be involved in memory impairment via modulating the NMDA receptor in STZ induced memory impaired rats.