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In addition, upregulation of NO synthesis by inducible nitric oxide synthase (iNOS) may induce injury and self-destructive processes.
The oxidative/nitrative stress and inflammation induce injury after myocardial ischemia/reperfusion.
High glucose concentration can induce injury of podocytes and berberine has a potent activity against diabetic nephropathy.
Intimate proximity of the liver to the small intestines and blood circulation exposes it to many foreign substances or their metabolites which may induce injury [1].
Although indispensable in the support of ARDS patients, artificial ventilation involves the application of mechanical forces to the lung parenchyma that can further induce injury [2], adding morbidity and mortality [3].
The presence of the rib cage presents a problem, since the high attenuation of the ribs results in a loss of power at the focus, and reflection of the beams may induce injury to the overlying soft tissues and the skin, which may also happen when US encounters an air-filled bowel loop.
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Fig. 1 HCA inhibits bronchial epithelial stretch-induced injury.
The current study also confirms that BD induces injury in other transplantable organs in sheep.
Renal IRI induced injury in remote organs including the lung and the contralateral kidney.
In addition, Ang II induces injury, oxidative stress and inflammation and impaired Nrf2 activation in HK-2 cells and podocytes.
Consistently, pre-treatment with antioxidant (Mitochondria-targeted antioxidant 10- 6-plastoquinonyl) decyltriphenyl-phosphonium) prevented ischemia induced injury (Plotnikov et al., 2008).
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