Sentence examples for induce fate from inspiring English sources

These results suggest that Ldb1-Lhx1 transcomplexnal complex is able to induce fate transformation of cells from the paraxial mesoderm to contribute to the intermediate mesoderm and adopt a pronephric kidney fate.

If the VPC was induced to give rise to more than 4 vulval progeny (Pn.pxxx cells), it was considered fully induced and assigned an 'I' (induced) fate [includes 1° and 2° fates as described previously (Sternberg and Horvitz 1986)].

We further discuss how mechanical factors have only recently been used to induce tenogenic fate in stem cells.

Ectopic expression of key regulatory genes is an important tool to study mechanisms of differentiation and to induce cell fate specification in hESCs.

The gene for the transcription factor Sry is located on the Y chromosome and is sufficient to induce testis fate in the bipotential gonad [1], [2], [3].

At early blastula stages, Wnt signals inhibit neural and induce epidermal fate by promoting BMP signaling [28], [29], raising the possibility that Wnt signals induce neural crest character in prospective forebrain cells by up-regulating BMP activity.

As early gastrula anterior endoderm is required for efficient cardiogenesis in Xenopus embryos and explants [2], we examined its ability to induce cardiac fate in pluripotent animal caps, which normally give rise to ectodermal derivatives and acquire an epidermal character when cultured alone.

Interestingly we also demonstrated that SCL and LMO2 are sufficient to induce hematopoietic fate in embryonic but not adult fibroblasts.

In the mouse, PRMT5 has been hypothesised to induce germline fate as an interactor of BLIMP1 (Ancelin et al, 2006).

We then cultured embryos in saturating doses of FGF4, which induce PrE fate throughout the ICM (Yamanaka et al., 2010).

Hlx1 alone was not sufficient to induce SC fate because hlx1-RNA-injected donors contributed to the DLAV and ISV stalk positions with a similar frequency as controls.