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Hypoxia and pro-inflammatory cytokines activate hypoxia-inducible factor to induce expression of Epo and EpoR.
We next tested whether a knockdown of Polycomb-group gene products could induce expression of Col4a1.
Consistently, TSA did not induce expression of Prdm1 in Th1 cells (Supplementary Fig. 4a).
Styrylquinolines induce expression of Cdr1p, as confirmed by Western blotting.
Grunfeld, C. et al. Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters.
This compound could induce expression of BCL6 target genes and kill BCL6-positive DLBCL cell lines.
Our data provides the first evidence that a cytokine can induce expression of BST-2, independently of type I IFN intermediates.
Such inhibition is known to induce expression of the ER and mitochondrial stress markers for the unfolded protein response (UPR)14, 15.
Furthermore, Greenwell-Wild et al. showed IL-27 could induce expression of the type I IFN-responsive, anti-viral APOBEC family of cytidine deaminases5.
IPTG (final 0.1 mM) was added to the culture medium to induce expression of GST-3MST or GST, and culture was continued for 21 hr at 20 °C.
Saren, P., Welgus, H.G. & Kovanen, P.T. TNF-α and IL-1β selectinduceinducexpressionof of 92-kDa gelatinase by human macrophages.
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