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We confirmed that only the CD11c+ DCs were able to induce division and CFSE dilution by adult OT-I cells (Fig. S1).
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Elevated levels of ROS disrupt ISC proliferation patterns by inducing division at a rate that surpasses EB differentiation, which leads to accumulation of polyploid aggregates, decreased intestinal integrity and accelerated mortality [ 5, 17, 18, 25].
This bacterium is a natural genetic engineer and transfers a part of its large Ti plasmid into host plants to induce cell division and the synthesis of opines.
To further assess whether CYCD regulates cell division in the QC, we tested whether ectopic expression of CYCD3 3 in the QC would be sufficient to induce cell division.
He points out that BrdU can induce cell division, and also labels dying cells, which synthesize DNA just before they die, so cannot give accurate counts of newborn cells in adult brain tissue.
This data shows that adenovirus-delivered Plk1 was able to induce cell division in proliferative cells.
We conclude that, in contrast to Cdc2/Cyclin B1 over-expression, the forced expression of Plk1 in adult cardiac myocytes is not sufficient to induce cell division and myocardial repair.
Using this system, we found that MYC's ability to induce mitotic division and tumorigenesis in the liver is developmentally regulated [26].
To investigate the role of Plk1 in nuclear and cellular division in rat cardiac myocytes, we over expressed wild type and constitutively active Plk1 in adult myocytes for 48 hours in the absence or presence of serum to determine whether Plk1 activity could induce cell division.
Moreover, ectopic expression of CYCD3 3 in the QC is sufficient to induce cell division in the QC.
Both cytokines signal through the same macrophage/microglia receptor (CSF-1R) and not only induce cell division of microglia and critically affect their development, maturation and survival [ 47].
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