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Polyphenolic compounds generate free radicals and other oxygen-based reactive species, which can induce considerable damage and toxicity [75].
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A metabolite of efavirenz is a potent neurotoxin in vitro, evoking calcium flux in neurons and inducing considerable damage to dendritic spines.
The study was performed in association with the 161-km Western States Endurance Run (WSER) since this race is known to induce considerable muscle damage and pain [2, 3, 5 7, 28 32].
An earthquake of 5 on the Richter scale can cause considerable damage, while one measuring 6 can cause severe damage.
Frequent typhoons in late summer and autumn cause considerable damage.
This energy can cause considerable damage during an earthquake.
As a result, poor mentoring can cause considerable damage.
Storm water control: Floods cause considerable damage in the region.
The news media are free from direct government control, but subsidies and licensing induce considerable self-control.
In particular, real-time feedback on a specific, energy-intensive activity may induce considerable behaviour change and savings.
In contrast, acriflavine (0.025%) induced considerable cellular DNA damage with illumination at 488 nm for 2 minutes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com