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For intracellular delivery siRNA into activated endothelial cells, formulation with SAINT-C18 was a necessity to induce a specific down-regulation of gene expression of VE-cadherin.
Theoretically, movement is incompatible with tonic immobility and will, of necessity, induce a change of mind-body state.
Their high rate of migration in the normal bile duct of the pig suggests the necessity to induce a stricture before placement.
The very same gene, when duplicated, induces a similar disorder, indicating the necessity of tight MECP2 regulation.
In fact, 25°C could already correspond to a value below the thermoneutral zone in aged animals and thus induce the necessity for water savings.
Nowadays, chemical treatments are widely used but the increasingly restrictive environmental regulations induce the necessity to take the environmental aspect into account in the choice of a suitable treatment.
Uehara induced a groundout.
Although Atg7 mutant flies are morphologically normal, they are sensitive to stressful conditions and show a decreased level of cell death-induced autophagy during metamorphosis, a necessity during normal development [23].
Some environments make shampoo a necessity.
The simultaneous satisfaction of the two above constrains induces the necessity to load the reactor with a huge mass of fuel; that is accomplished by equipping the fuel pins with the JAERI TRISO particles.
This new trend induces the necessity for better particle capture equipment and has made the environmental control equipment market increase by 20% in the last few years (Rocha et al., 2012).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com