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Although the tumoral HeLa cells are unable to undergo spontaneous replicative senescence, we found that RAC3 knockout by transfection with a siRNA induce a diminished replicative rate as compared with control scrambled-transfected cells.
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But it is also overcooked and frenetic, with some visual tricks and gimmicks repeated often enough to induce a diminishing return of novelty and effect.
Results show that the addition of the essential oil of the plant to the medium induces a diminish in the rate of corrosion and augmentation in the inhibitory efficiency of the oil.
Therefore, the question that remains is whether the infants, when maternal antibody levels have diminished, are able to induce a sufficient immune response or are they at that moment at risk for severe RSV illness.
Overall, there was excellent concordance as to whether the gene candidate was induced or diminished between the array and qRT-PCR results.
Nevertheless, it is conceivable that the phosphorylation of Ser-577/581 disturbs these interactions, for example, by inducing a conformational change which diminishes the binding of the kinases to B-Myb.
HK also induced a strong antimutagenic effect, significantly diminishing the mutagenicity of 2-AF in TA102 with metabolic activation, in a dose-dependent manner, by 42 to 52%;.
Third, the objectives of treatment (for example, reducing pain, diminishing anxiety, inducing a better sleep rhythmicity, treating delirium, and so on) must be clearly defined in order to choose the appropriate drug.
In addition, it has also been shown that under conditions that cause prolonged release of low amounts of ATP, this nucleotide has a more subtle modulatory function, inducing a distorted DC maturation and diminishing the ability of mature DCs to initiate type 1 immune responses.
As VCR treatment did not induce proliferation blockade, diminishing the tumor aggregates was not caused by a reduced cell growth rate.
Furthermore, distractors induced diminished activation (i.e., deactivation) in the middle and inferior occipital gyri at high load.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com