Suggestions(1)
Exact(38)
Eligible individuals were randomized (1 : 1) with a simple randomization procedure based on computerized random numbers to receive: LPV/r (Aluvia; Abbott Laboratories) 800/200 mg/day [taken daily (q.d). or twice daily (b.i.d). at the patient choice] or NVP 200 mg b.i.d.
Eligible individuals were randomized to intervention or control using permuted blocks with randomized block sizes 2, 4, 6, or 8 to ensure equal numbers in both groups.
Cluster randomization avoids spillover effects, which would have occurred if individuals were randomized and treated within the same practice.
The individuals were randomized into treatment or control groups based on their date of birth.
Individuals were randomized into either an intervention group that received standard exercise and nutrition information plus up to five face-to-face counseling sessions over 6 months, or into a control group that only received the standard information.
31 healthy individuals were randomized to receive single-sessions of true or sham HF-rTMS delivered to the left inferior frontal gyrus – a component of the human mirror system.
Similar(22)
Second, in a more subtle, but related, situation individuals are randomized in a traditional randomized trial, but naturally fall within a cluster (i.e patients are seen by a single physician) that leads to similarity in behavior (i.e. individual physician practice pattern leads to similar outcomes among patients) [ 43, 44].
Attrition, which leads to missing data, is a common problem in cluster randomized trials (CRTs), where groups of patients rather than individuals are randomized.
The term "cluster randomization" describes a procedure whereby clusters of individuals rather than single individuals are randomized to different treatment groups, often within a nationwide registry.
Cluster randomized trials, where individuals are randomized in groups are increasingly being used in healthcare evaluation.
Cluster randomized trials (CRTs), where groups of participants rather than individuals are randomized, are increasingly being used in health promotion and health services research [ 1].
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