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However, a total sample of 194 individuals was sufficient for the validation procedure.
If it transpired that the pre-pandemic vaccine was highly effective (VE 70%), the cohort of immune individuals was sufficient to prevent the pandemic, and pre-vaccination alone was then highly cost effective.
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Our results show that even seemingly small differences in blood glucose, such as the natural variations within a group of similar individuals, are sufficient to warrant careful attention to glucose correction when making quantitative comparisons.
Innate immunity of the respiratory system in normal individuals is sufficient to prevent P. aeruginosa infection, but is unable to eradicate the bacteria in immunodeficient individuals, resulting in recurrent infection or acute dissemination.
Stochastic model results (Figures 2 & 3) suggest that enhancement of epidemic duration is common throughout this region of parameter space, whereas enhancement of epidemic size is only observed where equilibrium populations of infectious individuals are sufficient to allow long-term persistence without stochastic extinction.
Although it is not known with certainty what type of contact between two individuals is sufficient for transmission of a pathogen, it has been shown that conversational contacts or social contacts in close proximity are a good proxy for contacts leading to transmission [5].
If we accept accuracies of 0.7 – 0.8, ~1*Ne*L training individuals is sufficient.
A relatively small number of individuals is sufficient, but more individuals still provide tangible benefits for data sets using less loci.
The results show that coancestry between only a few individuals is sufficient to detect exogenous genetic material and to remove it.
Work by Long and Langley [ 19] indicates that on the order of 500 individuals are sufficient to detect the presence of causative polymorphisms having small effect on outcomes.
Garza and Williamson (2001) recommend that sampling approximately 25 diploid individuals is sufficient for most vertebrate populations, although they indicate that there are no clear guidelines for determining an adequate sample size.
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