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Kv1.1 expression was also verified in human islets from three non-diabetic individuals by microarray (Affymetrix, results not shown).
We determined the expression profiles in skeletal muscle from people with type 2 diabetes, first degree relatives, and healthy control individuals by microarray experiments.
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67 However, recent large population studies of individuals tested by microarray analysis have shown that the frequency of reciprocal duplications is higher than in previous studies with other cytogenetic technologies.
Our study is also limited by the fact that the measurement of gene expression of individual genes by microarray is inevitably influenced by a number of factors, like oligo design and the continuous updates of the human genome sequence.
Pre- and post-resveratrol/GP expressions of individual genes by microarray were compared for all participants at each dose level on the clinical protocol with a two-tailed paired t-test.
Based on our results, we show that C3 deficiency is present already at birth and it is possible to identify the deficient individuals both by microarrays and sandwich ELISA using DBSS eluates.
EVA functions to screen microarray data individual-by-individual in search for any extreme values that may signify some abnormality.
The ND4L T10652C variant was confirmed by direct sequencing of mtDNA for the highest heteroplasmic individual (81% C heteroplasmy by microarray calculation) within the D1 haplogroup who was an MDD subject and had the C allele (Fig. 2).
Expression ratios for individual genes were examined by microarray analyses (see Supporting Information, Table S1).
14 Given that, on average, only 30%to40%0% of expressed genes in any individual tissue are detected by microarray technologies, 32 our transcriptome complement was, therefore, a reasonable representation of robustly detectable and actively transcribed genes within the technical limitations of this methodology.
Of these previously reported subtelomeric deletions, five individuals have been well characterized by microarray analysis [7] [9], [11].
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