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Preliminary results from longitudinal studies of individuals ascertained initially in a prodromal (i.e., "clinical high-risk") state appear to be interpretable within this framework.
The preliminary study group consisted of individuals ascertained exclusively at Vanderbilt (N = 393).
As a final check of how well the models would apply in population-based data, we removed all individuals ascertained in the ARMA cohort who were not part of the Health ABC Study.
Two different samples were obtained in the South region: (i) 189 individuals ascertained from blood donors in Porto Alegre, Rio Grande do Sul (RS - Fig. 1), were not self-identified, but rather had their color assigned by the health professionals who collected their samples, as White (n = 82), Brown (n = 78) or Black (n = 29).
Penetrance is usually estimated by examining individuals ascertained as having the disorder in question.
This issue can only be addressed via empirical investigation to establish the rates of ZDHHC9 mutations amongst individuals ascertained for different epilepsy syndromes.
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Further research is needed to understand the process by which individuals ascertain their partners' HIV serostatus and to identify those factors which enter into condom use decisions.
In [1], the authors propose a privacy protecting video surveillance system which utilizes RFID sensors to identify incoming individuals, ascertains their privacy preference specified in an XML-based privacy policy database, and finally uses a simple video masking technique to selectively conceal authorized individuals and display unauthorized intruders in the video.
In order to assess the benefits of transethnic GWAS for the detection and fine-mapping of novel loci for complex traits, I have repeated simulations of the transethnic fixed-effect model under two scenarios: (i) 11 GWAS of 1,000 individuals, each ascertained from a different HMP3 population; and (ii) 11 GWAS of 1,000 individuals, each ascertained from the same CEU population.
The individuals were ascertained in the Municipal Health Clinic in the Sacramenta area of the city of Belém, Pará and self-identified as White (n = 66; 33%), Brown (n = 65; 32%) or Black (n = 72; 35%).
Absence of close relationships between the individuals was ascertained through interview data.
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