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Each class was individually refined to reach resolutions of 4.3 Å or 4.6 Å.
The individually refined models were then docked into the maps of the full KATP channel and refined respectively.
Averages aligned against reference A were individually refined for each tomogram.
In order to increase the signal present in the raw frames, 3-frame sums of the motion corrected particles were calculated, and these sub-sums were individually refined using Frealign again using data between 200 Å and 15 Å.
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Registry and other errors to the ribosomal proteins were corrected manually, and each chain was refined individually against an appropriately cut map.
In such situations, the community as a whole develops and constructs new knowledge while the community members also individually advance and refine their own knowledge.
Missing covariate patterns were individually explored and imputation equations refined.
Participants brainstormed "troublesome" concepts in biochemistry individually and then discussed and refined their ideas in small groups.
Alignments and phylogenies were repeatedly refined for each orthologous group individually.
The model contains two independently refined DC8E8 Fab molecules and eight water molecules, which were individually checked for a reasonable electron density and correct hydrogen bonding.
A recent research study carried out by McKinsey & Co and sponsored by Internet.org identifies the aforementioned issues, as well, but mentions them individually instead of further refining them into demand- or supply-side problems.
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