By 2004, regulators imposed tougher rules under which records could be wiped clean only if an arbitration panel found that an investor's allegations had been factually impossible or false, or that the accused broker had not been individually involved in the matter.
Furthermore, the signal decoding complexity individually involves each femtocell that requests interference cancellation, in contrast to the schemes in[7, 14].
This suggests that the PRD and MTBD are individually involved in DNA binding.
To further explore high-order gene-environment interactions that were individually involved in cervical cancer risk, we performed the MDR analysis, as described previously [ 17, 18].
Lee et al. [ 3] compared their data against a longevity surface compiled from previously published studies, individually involving many fewer dietary treatments and no measurement of long-term food intake.
It has been shown in literature that all three histone-modifying enzymes, analyzed in our study, are individually involved in inhibition of functioning of p53 via direct modification of p53 (demethylation by LSD1 [ 25] and deacetylation by SIRT1 [ 26]) or inhibition of p53-DNA binding (HDAC2 [ 27]).
By comparing the wildtype OH11 with mutant strains having a single lsp gene or a combination of lsp genes deleted, we found that each Lsp protein individually is involved in positive regulation of HSAF and WAP-8294A2 biosynthesis, but the proteins collectively do not exert additive effects in this regulation.
Bax or Bak reconstitution sensitized Bax−/−/Bak−/− MEFs to NO-induced apoptosis indicating that these proteins, individually, are involved in this pathway (Figure 2A C).
In addition, the mechanism is in accord with a recent investigation demonstrating that phosphorylated Y429, Y431, and Y479 in the EPOR cytoplasmic domain bind the p85 subunit of PI3 kinase on EPO stimulation and individually are involved in mediating EPO-dependent EPOR internalization [36].
Similarly, many genes recognised individually as involved in modulating phagosomal maturation e.g. sapM [ 99], PE_PGRS62 [ 100], PE_PGRS30 [ 101], eis [ 102] also had fitness costs.
